Is my wife pregnant?

Let me preface this that I have no worries about the fidelity of my wife, I trust her completely.

My wife has been away with an internship since May 6th, and as we were treasuring our last days together I was keen to know when her period began as we are not ready to start that part of a family yet. A week or two go by and she gets her period (around the middle of May).

She then does not get her June (nor July nor August) period, though she takes a home pregnancy test when her period should have started in June and one two weeks after that and both were negative.

Since then she has had a few other symptoms; for a weekend she had lower back pain and nausea, alternating constipation and diarrhea, fatigue, cramps.

She has an appointment with her OB-GYN tomorrow but my mind is going for a loop and any input would be appreciated.

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